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The nature of the tissue changes can vary from simple erythema (redness) / hyperaemia (increased blood flow) of the mucosa in 18% of cases, [1] to a chronic-appearing, small, shallow ulcer with nodular margins and a white or sloughing base. [8] [1] In up to 33% of cases there is no ulceration but instead one or more well-developed polyps or ...
Solitary rectal ulcer syndrome (SRUS) is a rare benign disease characterized by symptoms, clinical findings, and histological abnormalities. [9] Only 40% of patients have ulcers; 20% of patients have a single ulcer, and the remaining lesions range in size and form from broad-based polypoid to hyperemic mucosa. [10]
PPCS is caused by an electrocautery-induced injury to the wall of the colon that occurs during removal of colon polyps. [3] PPCS occurs when the electric current extends beyond the mucosa, entering the muscularis propria and serosa, resulting in a full thickness (transmural) burn injury. [ 1 ]
Traditional serrated adenoma seen under microscopy with H&E stain, showing serrated crypts. SPS may occur with one of two phenotypes: distal or proximal. [6] The distal phenotype may demonstrate numerous small polyps in the distal colon and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). [6]
This provocative study demonstrates that biological age, which can be evaluated by a blood test, is associated with a higher incidence of precancerous colon polyps.” — Anton Bilchik, MD, PhD ...
While colon polyps are not commonly associated with symptoms, occasionally they may cause rectal bleeding, and on rare occasions pain, diarrhea or constipation. [9] They are a concern because of the potential for colon cancer being present microscopically, and the risk of benign colon polyps becoming malignant over time. [ 10 ]
Polyps are either pedunculated (attached to the intestinal wall by a stalk) or sessile (grow directly from the wall). [5] [6]: 1342 In addition to the gross appearance categorization, they are further divided by their histologic appearance as tubular adenoma which are tubular glands, villous adenoma which are long finger like projections on the surface, and tubulovillous adenoma which has ...
Polyps over 10mm may have to be removed piecemeal by snare polypectomy. The use of electrocautery over a large area has a significant risk of causing colonic perforation; to reduce this chance, and to facilitate the polypectomy, sterile fluid (saline or colloid, with methylene blue dye added) can be injected under the base of the polyp to raise ...