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Hidradenitis suppurativa (HS), sometimes known as acne inversa or Verneuil's disease, is a long-term dermatological condition characterized by the occurrence of inflamed and swollen lumps. [ 2 ] [ 3 ] These are typically painful and break open, releasing fluid or pus . [ 3 ]
First line treatment includes topical and intralesional glucocorticoids. Specific therapies include estrogen hormones and steroid creams. Use of tretinoin reduced pruritic and axillary papules in one study. However, irritation limited drug use to short term only. Clindamycin mixed with pimecrolimus cream and benzoyl peroxide was also effective.
Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. [5] [6] [7] It is also under development in a higher concentration for the treatment of androgen-dependent scalp hair loss, under the brand name Breezula. [6]
Ichthammol or ammonium bituminosulfonate (brand name Ichthyol), also known as black ointment, is a medication derived from sulfur-rich oil shale (bituminous schists). It is used (sometimes in combination with zinc oxide ) as a treatment for different skin diseases , including eczema and psoriasis (see below).
Psoriasis, eczema, hidradenitis suppurativa and scleroderma are just a few of the skin conditions that are fueled by underlying inflammation, research shows. skynesher - Getty Images Fatigue
Hidradenitis suppurativa is a chronic cutaneous condition originally thought to be primarily characterized by suppurative inflammation of the apocrine sweat glands. [ 3 ] : 710 Recent evidence supports that the primary event is follicular hyperkeratosis and obstruction, [ 4 ] but the term hidradenitis supperativa has continued to be used in ...
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