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  2. Chronic multifocal Langerhans cell histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Chronic_multifocal_Langer...

    Features relating to lung and liver disease may occur. [1] [5] It is due to a genetic mutation in the MAPKinase pathway that occurs during early development. [1] The diagnosis may be suspected based on symptoms and MRI and confirmed by tissue biopsy. [6] [7] Blood tests may show anaemia, and less commonly a low white blood cell count and low ...

  3. Langerhans cell histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Langerhans_cell_histiocytosis

    With multi-focal disease 60% have a chronic course, 30% achieve remission and mortality is up to 10%. [48] A full recovery can be expected for people who seek treatment and do not have more lesions at 12 and 24 months. However, 50% of children under 2 with disseminated Langerhans cell histiocytosis die of the disease.

  4. List of childhood diseases and disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_childhood_diseases...

    The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:

  5. Human T-lymphotropic virus 1 - Wikipedia

    en.wikipedia.org/wiki/Human_T-lymphotropic_virus_1

    The symptoms of ATL were different from other lymphomas known at the time. The common birthplace shared amongst most of the ATL patients was suggestive of an infectious cause, referred to as ATLV. [5] Strikingly, ATLV had the transforming activity in vitro. [6] These studies established that HTLV-1 was the causitive agent of ATL.

  6. Childhood chronic illness - Wikipedia

    en.wikipedia.org/wiki/Childhood_chronic_illness

    Chronic diseases in children may have a genetic (hereditary) cause, an environmental (acquired) cause or a combination of both. Early identification and treatment of the disease is key to successful health outcomes. Chronic diseases can affect multiple organ systems and can, therefore, manifest in different ways.

  7. Myotonia congenita - Wikipedia

    en.wikipedia.org/wiki/Myotonia_congenita

    Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder.The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1]

  8. Bobble-head doll syndrome - Wikipedia

    en.wikipedia.org/wiki/Bobble-head_doll_syndrome

    In the case of choroid plexus papilloma, surgical removal of the cyst-containing lesion from within the third ventricle caused a full recovery. The mobile nature of the cystic lesion led to its intermittent obstruction of the foramen of Monro and proximal aqueduct, producing the bobble-head symptoms. Once removed, all symptoms disappeared. [5]

  9. Alternating hemiplegia of childhood - Wikipedia

    en.wikipedia.org/wiki/Alternating_hemiplegia_of...

    Paroxysmal symptoms include tonic, tonic–clonic, or myoclonic limb movements, [8] dystonic posturing, choreoathetosis, ocular nystagmus, and various other ocular motor abnormalities. [1] [6] Almost half of all people have dystonic symptoms prior to experiencing hemiplegia. [4] These symptoms generally begin before 8 months of age. [8]