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Underexcretion of uric acid by the kidney is the primary cause of hyperuricemia in about 90% of cases, while overproduction is the cause in less than 10%. [5] About 10% of people with hyperuricemia develop gout at some point in their lifetimes. [19] The risk, however, varies depending on the degree of hyperuricemia.
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C 5 H 4 N 4 O 3.It forms ions and salts known as urates and acid urates, such as ammonium acid urate.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
The protein encoded by this gene is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. This protein is an integral membrane protein primarily found in kidney.
The basis of the division of verses is the Quranic passage: [1] He it is Who has revealed the Book to you; some of its verses are decisive (Muhkam), they are the basis of the Book, and others are allegorical (Mutashabih); then as for those in whose hearts there is perversity they follow the part of it which is allegorical, seeking to mislead and seeking to give it (their own) interpretation ...
At-Tawbah (Arabic: ٱلتوبة, lit. 'the Repentance') is the ninth chapter of the Quran.It contains 129 verses and is one of the last Medinan surahs.This Surah is known by two names, At-Taubah and Al-Bara'at.
9–10: In this verse "the one who discourages" references Abu Jahl when he tried to stop Muhammed from making devotions towards Allah, and anyone else for that matter. [ citation needed ] 11–14: These verses question whether the "one who discourages" is being "guided" or even "concerned" about God.
Although the term al-ʿashara al-mubashsharūn (sometimes also al-mubashshara, [1] both meaning 'the ten to whom glad tidings were given') itself dates from a period after the 9th century, [10] the list of ten as such already appears on an inscription made upon a plaster table which is thought to have belonged to the palace of Khalid al-Qasri, an Umayyad official who served as the governor of ...