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Injection site reactions (ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration.
Aphthous stomatitis, [2] or recurrent aphthous stomatitis (RAS), commonly referred to as a canker sore or salt blister, is a common condition characterized by the repeated formation of benign and non-contagious mouth ulcers (aphthae) in otherwise healthy individuals.
Diagramatic representation of mucosal erosion (left), excoriation (center), and ulceration (right) Simplistic representation of the life cycle of mouth ulcers. An ulcer (/ ˈ ʌ l s ər /; from Latin ulcus, "ulcer, sore") [2] is a break in the skin or mucous membrane with loss of surface tissue and the disintegration and necrosis of epithelial tissue. [3]
Canker sore that wouldn't heal turned out to be stage 4 tongue cancer. Tongue cancer used to affect older men, who drank, smoke. More people under 40 have it.
Relief of skin pain caused by sunburn, ingrown toenails, hemorrhoids, [5] Examples of combination medications of benzocaine include: Antipyrine-benzocaine otic consists of antipyrine and benzocaine, and is used to relieve ear pain and remove earwax. [6] Cepacol consists of menthol and benzocaine, and is used to treat sore throat. [7]
Aphthous stomatitis (canker sores) is the recurrent appearance of mouth ulcers in otherwise healthy individuals. The cause is not completely understood, but it is thought that the condition represents a T cell mediated immune response which is triggered by a variety of factors.
This test is typically performed by an allergist who uses a skin-prick and intradermal injection of penicilloyl-polylysine, a negative control (normal saline), and a positive control . [ 8 ] A small proportion of people who are allergic to penicillins also have similar cross sensitivities to other antibiotics such as cephalosporins .
Sulfonated phenolics/sulfuric acid appears to be more effective on sores in areas of the mouth that produce less saliva. Since a sore must be dry prior to application of Debacterol, it is difficult to properly apply under the tongue. The duration of pain relief and the overall effectiveness may be reduced in such areas. [citation needed]
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