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A calibration curve plot showing limit of detection (LOD), limit of quantification (LOQ), dynamic range, and limit of linearity (LOL).. In analytical chemistry, a calibration curve, also known as a standard curve, is a general method for determining the concentration of a substance in an unknown sample by comparing the unknown to a set of standard samples of known concentration. [1]
The LoQ is the limit at which the difference between two distinct signals / values can be discerned with a reasonable certainty, i.e., when the signal is statistically different from the background. The LoQ may be drastically different between laboratories, so another detection limit is commonly used that is referred to as the Practical ...
Process performance qualification protocol is a component of process validation: process qualification.This step is vital in maintaining ongoing production quality by recording and having available for review essential conditions, controls, testing, and expected manufacturing outcome of a production process.
Pharmaceutics deals with the formulation of a pure drug substance into a dosage form.Pure drug substances are usually white crystalline or amorphous powders. Before the advent of medicine as a science, it was common for pharmacists to dispense drugs as is.
Pharmaceutical engineering is a branch of engineering focused on discovering, formulating, and manufacturing medication, analytical and quality control processes, and on designing, building, and improving manufacturing sites that produce drugs.
Technology, which is transforming science, medicine, and research tools has increased the speed at which we can analyze data but we currently still must test the products which is a lengthy process. [3] Differences in the performance of medical care may be due to variation in the introduction and circulation of pharmaceutical innovations. [4]
Lab-on-a-chip technology may soon become an important part of efforts to improve global health, [26] particularly through the development of point-of-care testing devices. [27] In countries with few healthcare resources, infectious diseases that would be treatable in a developed nation are often deadly.
Laboratory informatics is the specialized application of information technology aimed at optimizing and extending laboratory operations. [1] It encompasses data acquisition (e.g. through sensors and hardware [2] or voice [3] [4] [5]), instrument interfacing, laboratory networking, data processing, specialized data management systems (such as a chromatography data system), a laboratory ...