Search results
Results from the WOW.Com Content Network
The process known as "molecular mimicry" occurs when an infectious organism that shares epitopes from its host's afflicted tissue triggers an immune response in the host. However, only a small number of convincingly identified specific targets for such a response have been found in chronic inflammatory demyelinating polyneuropathy.
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
However, in a person with MS, these cells recognize healthy parts of the central nervous system as foreign and attack them as if they were an invading virus, triggering inflammatory processes and stimulating other immune cells and soluble factors like cytokines and antibodies. Many of the myelin-recognizing T cells belong to a terminally ...
MS is an inflammatory demyelinating disease of the central nervous system (CNS) that develops in genetically susceptible individuals after exposure to unknown environmental trigger(s). The bases for MS are unknown but are strongly suspected to involve immune reactions against autoantigens, particularly myelin proteins.
Virus infections usually begin in the peripheral tissues, and can invade the mammalian system by spreading into the peripheral nervous system and more rarely the CNS. CNS is protected by effective immune responses and multi-layer barriers, but some viruses enter with high-efficiency through the bloodstream and some by directly infecting the ...
CIDP Chronic inflammatory demyelinating polyneuropathy: CIPA Congenital insensitivity to pain with anhidrosis: CIP Congenital insensitivity to pain: CJD Creutzfeldt–Jakob disease: CKD Chronic kidney disease: CLOVES syndrome Congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal/spinal abnormalities syndrome CML
Guillain–Barré syndrome (also called "GBS") is a rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. [3] Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. [3]
Viral causes of neuritis include herpes simplex virus, varicella zoster virus, and HIV. Leprosy is frequently characterized by direct neural infection by the causative organism, mycobacterium leprae. [14] Leprosy presents with a heterogeneous clinical picture dictated by bacterial titer and inborn host resistance. [13]