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The Jurkat cell line (originally called JM) was established in the mid-1970s from the peripheral blood of a 14-year-old boy with T cell leukemia. [2] [3] Different derivatives of the Jurkat cell line that have been mutated to lack certain genes can now be obtained from cell culture banks.
Huh7 cells – hepatocyte-derived carcinoma cell line; Jurkat cells – a human T lymphocyte cell line isolated from a case of leukemia; OK cells – derived from female North American opossum kidney cells; Ptk2 cells – derived from male long-nosed potoroo epithelial kidney cells; Vero cells – a monkey kidney cell line that arose by ...
ZAP-70 was initially discovered in TCR-stimulated Jurkat cells, an immortal line of human T lymphocytes, in 1991. [6] Its molecular weight is 70 kDa , and it is a member of the protein- tyrosine kinase family and is a close homolog of SYK .
Among the most commonly used cell lines are HeLa and Jurkat, both of which are immortalized cancer cell lines. [4] These cells have been and still are widely used in biological research such as creation of the polio vaccine, [5] sex hormone steroid research, [6] and cell metabolism. [7] Embryonic stem cells and germ cells have also been ...
CD47 ligation leads to cell death in many normal and tumor cell lines via apoptosis or autophagy. The activation of CD47 induces rapid apoptosis of T cells. Jurkat cells and peripheral blood mononuclear cells incubated with the monoclonal antibody Ad22 results in apoptosis within 3 hours. However, apoptosis was not observed following culture ...
Between 1970 and 2002, the probability that a working-age American would unexpectedly lose at least half her family income more than doubled. And the danger is particularly severe for young people. In the 1970s, when the boomers were our age, young workers had a 24 percent chance of falling below the poverty line.
Pages in category "Human cell lines" The following 95 pages are in this category, out of 95 total. ... Jurkat cells; JY cell line; K. K562 cells; KBM-7 cells; KHYG-1 ...
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