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There is an alternative definition of fold change, [citation needed] although this has generally fallen out of use. Here, fold change is defined as the ratio of the difference between final value and the initial value divided by the initial value. For quantities A and B, the fold change is given as (B − A)/A, or equivalently B/A − 1. This ...
The population MAD is defined analogously to the sample MAD, but is based on the complete population rather than on a sample. For a symmetric distribution with zero mean, the population MAD is the 75th percentile of the distribution. Unlike the variance, which may be infinite or undefined, the population MAD is always a finite number.
Based on one definition, a drug-like molecule has a logarithm of partition coefficient (log P) between −0.4 and 5.6, molecular weight 160–480 g/mol, molar refractivity of 40–130, which is related to the volume and molecular weight of the molecule and has 20–70 atoms.
In its simplest form, the hazard ratio can be interpreted as the chance of an event occurring in the treatment arm divided by the chance of the event occurring in the control arm, or vice versa, of a study. The resolution of these endpoints are usually depicted using Kaplan–Meier survival curves. These curves relate the proportion of each ...
For example, in a study examining the effect of the drug apixaban on the occurrence of thromboembolism, 8.8% of placebo-treated patients experienced the disease, but only 1.7% of patients treated with the drug did, so the relative risk is 0.19 (1.7/8.8): patients receiving apixaban had 19% the disease risk of patients receiving the placebo. [4]
By definition, at Mach 1, the local flow velocity u is equal to the speed of sound. At Mach 0.65, u is 65% of the speed of sound (subsonic), and, at Mach 1.35, u is 35% faster than the speed of sound (supersonic). An F/A-18 Hornet creating a vapor cone at transonic speed just before reaching the speed of sound.
log 10 (3.000 × 10 4) = log 10 (10 4) + log 10 (3.000) = 4.000000... (exact number so infinite significant digits) + 0.477 1 212547... = 4.477 1 212547 ≈ 4.4771. When taking the antilogarithm of a normalized number, the result is rounded to have as many significant figures as the significant figures in the decimal part of the number to be ...
The Reynolds number Re is taken to be Re = V D / ν, where V is the mean velocity of fluid flow, D is the pipe diameter, and where ν is the kinematic viscosity μ / ρ, with μ the fluid's Dynamic viscosity, and ρ the fluid's density. The pipe's relative roughness ε / D, where ε is the pipe's effective roughness height and D the pipe ...