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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Studies have suggested the use of naltrexone in drug courts or healthcare rehabs is a form of "post-social control," [152] or "post-disciplinary control," [153] whereby control strategies for managing offenders and addicts shift from imprisonment and supervision toward more direct control over biological processes.
Naltrexone-bupropion. An FDA-approved weight loss medication, naltrexone-bupropion is generally considered effective and safe to use. You may experience side effects like dizziness, mood changes ...
Naltrexone-bupropion (Contrave®). This medication combines two drugs: bupropion (an antidepressant that may suppress appetite) and naltrexone, which is used to treat addiction. The combination is ...
Since bupropion is metabolized to hydroxybupropion by the enzyme CYP2B6, drug interactions with CYP2B6 inhibitors are possible: this includes such medications as paroxetine, sertraline, norfluoxetine (active metabolite of fluoxetine), diazepam, clopidogrel, and orphenadrine. The expected result is an increase of bupropion and a decrease in ...
“GLP-1 medications impact all of the neurotransmitters in the brain associated with mental health—norepinephrine, serotonin, and dopamine,” says Sue Decotiis, MD, a weight loss doctor based ...
“Naltrexone has a half-life of 5 hours, and extended-release bupropion has a half-life of 21 hours, whereas weekly dosed GLP-1 receptor agonist medications have a half-life of 7 days,” Rhodes ...
In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. [ 1 ] [ 2 ] Contraindication is the opposite of indication , which is a reason to use a certain treatment.
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