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Various calculations and methods are used to try to measure kidney function. Renal clearance is the volume of plasma from which the substance is completely cleared from the blood per unit time. The filtration fraction is the amount of plasma that is actually filtered through the kidney. This can be defined using the equation.
These include tests that are intended to directly measure the function of the kidneys, as well as tests that assess the function of the kidneys by looking for evidence of problems associated with abnormal function. One of the measures of kidney function is the glomerular filtration rate (GFR). Other tests that can assess the function of the ...
Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney. This encompasses all functions of the kidney, including maintenance of acid-base balance; regulation of fluid balance; regulation of sodium, potassium, and other electrolytes; clearance of toxins; absorption of glucose, amino acids, and other small molecules ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 5 February 2025. This article is about the human urinary system. For urinary systems of other vertebrates, see Urinary systems of birds, urinary systems of reptiles, and urinary systems of amphibians. Anatomical system consisting of the kidneys, ureters, urinary bladder, and the urethra Urinary system 1 ...
The severity of chronic kidney disease (CKD) is described by six stages; the most severe three are defined by the MDRD-eGFR value, and first three also depend on whether there is other evidence of kidney disease (e.g., proteinuria): 0) Normal kidney function – GFR above 90 mL/min/1.73 m 2 and no proteinuria
Serum creatinine (a blood measurement) is an important indicator of kidney function, because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced [ 5 ] via a biological system involving creatine , phosphocreatine (also known as creatine phosphate), and adenosine ...
The kidneys are susceptible to toxic injury, since toxins are reabsorbed in the tubules along with most of the filtered substances. [47] The kidneys are able to restore their functionality after acute injury, but it also can progress into chronic kidney disease. Chronic kidney disease is characterised by loss of function of the kidney tissues ...
The kidney's primary function is the elimination of waste from the bloodstream by production of urine. They perform several homeostatic functions such as:- Maintain volume of extracellular fluid; Maintain ionic balance in extracellular fluid; Maintain pH and osmotic concentration of the extracellular fluid.
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