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The Herxheimer reaction is a natural response to the destruction of harmful bacteria and other threatening microorganisms. If the reaction is exceedingly uncomfortable or severe, cessation or reduction of treatment may be warranted.
A Jarisch–Herxheimer reaction is a sudden and typically transient reaction that may occur within 24 hours of being administered antibiotics for an infection by a spirochete, including syphilis, leptospirosis, Lyme disease, and relapsing fever. [1]
What is a Herxheimer reaction? The Herxheimer reaction, also known as the Herx reaction or Jarisch Herxheimer reaction, is an immune response to endotoxins released by dying microbes.
The Jarisch Herxheimer Reaction (JHR) is a transient and reversible condition that can be clinically diagnosed with proper history and physical examination. However, there are reports of lymphopenia, polymorphonuclear leucocytosis, and raised ESR on laboratory analysis.
The Jarisch-Herxheimer reaction –often shortened just to “Herxheimer” or “herxing”—happens after you start antibiotic treatment for spirochetal infections like syphilis, Lyme disease, and tick-borne relapsing-fever.
What Is a Herxheimer Reaction? The Jarisch-Herxheimer Reaction, known colloquially as a Herxheimer Reaction or “herx” was discovered by dermatologists Adolf Jarisch and Karl Herxheimer in their studies of syphilis.
What is a Herxheimer reaction? The Jarisch-Herxheimer reaction was first identified by two dermatologists, Adolf Jarisch and Karl Herxheimer, while studying syphilis. It’s often colloquially referred to as simply a Herxheimer reaction, or a “Herx.”