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Hyperthermia therapy (or hyperthermia, or thermotherapy) is a type of medical treatment in which body tissue is exposed to temperatures above body temperature, in the region of 40–45 °C (104–113 °F). Hyperthermia is usually applied as an adjuvant to radiotherapy or chemotherapy, to which it works as a sensitizer, in an effort to treat cancer.
Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. [1]
Hyperthermia is generally diagnosed by the combination of unexpectedly high body temperature and a history that supports hyperthermia instead of a fever. [2] Most commonly this means that the elevated temperature has occurred in a hot, humid environment (heat stroke) or in someone taking a drug for which hyperthermia is a known side effect ...
The first step is to stop the culprit medication and treat the hyperthermia aggressively, such as with cooling blankets or ice packs to the axillae and groin. Acetaminophen is commonly used as an anti-pyretic. Supportive care in an intensive care unit capable of circulatory and ventilatory support is crucial.
This is a mixed modality medical simulation of the treatment of malignant hyperthermia by anesthesia residents. The residents are managing care, mixing dantrolene and utilizing a cognitive aid at the bedside. Fast recognition and treatment of MH utilizes skills and procedures that are utilized with a low-frequency and high-risk. [37]
Dantrolene, a muscle relaxant used to treat other forms of hyperthermia, is not an effective treatment for heat stroke. [25] Antipyretics such as aspirin and acetaminophen are also not recommended as a means to lower body temperature in the treatment of heat stroke and their use may lead to worsening liver damage. [5]
Heat stress can result in heat-related illnesses, such as heat stroke, hyperthermia, heat exhaustion, heat cramps, heat rashes, and chronic kidney disease (CKD). [2] [3] Although heat exhaustion is less severe, heat stroke is a medical emergency and requires emergency treatment, which if not provided, can lead to death. [4]
The Haddon Matrix is the most commonly used paradigm in the injury prevention field. Developed by William Haddon in 1970, the matrix looks at factors related to personal attributes, vector or agent attributes and environmental attributes; before, during and after an injury or death. By utilizing this framework, one can then think about ...