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Nicotine polacrilex is nicotine bound to an ion-exchange resin (polymethacrylic acid, such as Amberlite IRP64, Purolite C115HMR or Doshion P551). [4] It is added to gum and hard lozenges used for nicotine replacement therapy in smoking cessation , such as in the Nicorette range of products.
Nicotine gum is a chewing gum containing a small dose of nicotine polacrilex. [1] It is classified as a short-acting (also called fast-acting) form of NRT because it relieves the cravings and symptoms that occur with smoking cessation more quickly than a long-acting NRT (i.e., the nicotine patch).
Nicorette is the brand name of a number of products for nicotine replacement therapy (NRT) that contain nicotine polacrilex.Developed in the late 1970s in Sweden by AB Leo [] in the form of a chewing gum, Nicorette was the first nicotine replacement product on the market.
A nicotine lozenge is a modified-release dosage tablet (usually flavored) that contains a dose of nicotine polacrilex, which dissolves slowly in the mouth to release nicotine over the course of 20 to 30 minutes. Nicotine lozenges are intended to help individuals quit smoking and are generally an over-the-counter medication.
Using 4 mg nicotine gum versus 2 mg gum increases the likelihood of successful smoking cessation. [28] When using the gum, acidic beverages like soda, coffee, or beer should be avoided fifteen minutes prior and during use because they can impede proper absorption of nicotine. [33] Nicotine inhalers come in 10 mg and 15 mg cartridge strengths ...
Nicotine is unusual in comparison to most drugs, as its profile changes from stimulant to sedative with increasing dosages, a phenomenon known as "Nesbitt's paradox" after the doctor who first described it in 1969. [135] [136] At very high doses it dampens neuronal activity. [137] Nicotine induces both behavioral stimulation and anxiety in ...
Zyn pouches are sold in round cans containing 15 or 20 pouches depending on the market. Pouches are available in different levels of nicotine strength (such as 3 or 6 milligrams per pouch in the US) and different flavored and unflavored varieties. [17] The pouches contain nicotine extracted from tobacco leaves, and food grade ingredients. [18]
Tobacco gum, like dissolvable tobacco, is a recent introduction - a type of chewing gum which, like nicotine gum provides nicotine through oral absorption. However, the difference between nicotine gum and tobacco gum is that tobacco gum is made from finely powdered tobacco mixed with a gum base, rather than freebase nicotine. Example of products:
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