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Kligman formula consisting of 0.1% tretinoin, 5.0% hydroquinone, 0.1% dexamethasone, and hydrophilic ointment. [12] The dermatologist gold-standard formula for treating hyperpigmentation is the Kligman formula, a prescription named after its inventor, dermatologist Dr. Albert Kligman. It was originally formulated in 1975 and has remained the ...
Hydroquinone is a commonly used agent in skin whiteners. The European Union banned it from cosmetics in 2000. [9] It works by decreasing melanin production. [9] Tretinoin, also known as all-trans retinoic acid, may be used to whiten specific areas. [6] It may be used in combination with steroids and hydroquinone. [6]
The origin of the name tretinoin is uncertain, [42] [43] although several sources agree (one with probability, [42] < one with asserted certainty [44]) that it probably comes from trans-+ retinoic [acid] + -in, which is plausible given that tretinoin is the all-trans isomer of retinoic acid. The name isotretinoin is the same root tretinoin plus ...
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne. [1] [2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent. [3] The combination was approved for medical use in the United States in July 2021. [2] [4] [5]
Clindamycin/tretinoin is a topical gel used in the treatment of acne. The two active ingredients are the antibiotic clindamycin phosphate (1.2%) and tretinoin (0.025%), a retinoid . [ 1 ] The two active ingredients perform different functions, the clindamycin is active against gram-positive bacteria, including streptococci and penicillin ...
Mequinol is a common active ingredient in topical drugs used for skin depigmentation.As a topical drug mequinol is often mixed with tretinoin, a topical retinoid.A common formulation for this drug is an ethanolic solution of 2% mequinol and 0.01% tretinoin by mass. [1]
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C 6 H 4 (OH) 2. It has two hydroxyl groups bonded to a benzene ring in a para position.
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