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Sensory side effects include paresthesias, dysesthesias, numbness, altered proprioception, and loss of dexterity in fingers and toes. Motor and autonomic symptoms are less frequent but possible. Symptoms may start days after the patient receives their first dose of chemotherapy, are dose dependent, and tend to improve after completion of treatment.
Intensification chemotherapy is identical to consolidation chemotherapy but a different drug than the induction chemotherapy is used. [6]: 55–59 Combination chemotherapy involves treating a person with a number of different drugs simultaneously. The drugs differ in their mechanism and side-effects.
Chemo-protective agents are common drugs and like many other drugs, may have side effects of their own. Each agent has different side effects though the most common consist of dizziness, sleepiness, nausea, fever, etc. [ 3 ] It is important to discuss the side effects of these drugs with a doctor before using them to combat any type of ...
Chemo mouth is a common side effect of undergoing chemotherapy. Dr. Rajiv Saini of Texas discusses the symptoms, risks and best treatments for the harmful condition.
The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side effect. [9] Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival and reduce risk of recurrence. [ 2 ] In total, these drugs can cause a combination of more than 40 specific side effects which include neurotoxicity , which is manifested by peripheral neuropathies including polyneuropathy .
One philosophical justification for this approach is the doctrine of double effect, where to justify an act involving both a good and a bad effect, four conditions are necessary: [8] [59] the act must be good overall (or at least morally neutral) the person acting must intend only the good effect, with the bad effect considered an unwanted side ...
This effect could be due to precluding physical contact between client proteins and Hsp90. [6] So since the molecular chaperones are overexpressed in a wide variety of cancer cells and in virally transformed cells, inhibiting the function of these chaperones is essential to controlling cancer cells, as this would affect the activity of ...