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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
Emollient laxatives, also known as stool softeners, are anionic surfactants that enable additional water and fats to be incorporated in the stool, making movement through the bowels easier. Properties. Site of action: small and large intestines; Onset of action: 12–72 hours; Examples: Docusate (Colace, Diocto), Gibs-Eze [3]
Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM, BHPM).
Lactulose may be used to counter the constipating effects of opioids, and in the symptomatic treatment of hemorrhoids as a stool softener. [medical citation needed] Lactulose is commonly prescribed for children who develop fear of their bowel movements and are withholders.
A Temple University student was arrested at an Insomnia Cookie store. He and two other men are suspected of impersonating ICE agents.
Jessica Simpson is opening up about sobriety and songwriting.. In a cover story with sister Ashlee Simpson for The Cut, the "With You" singer spoke about songwriting and how drinking impacts the ...
Colace is the trade name for Docusate, the pharmaceutical compound dioctyl sulfosuccinate (DOSS), a laxative. Colace may also refer to: People.
Former Major League Baseball Commissioner Fay Vincent died Saturday, Feb. 1, at the age of 86, current commissioner Rob Manfred announced in a statement Sunday afternoon.