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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    They have a rapid onset and offset of action. This means it is often possible to pause them 12 to 48 hours before surgery and resume them shortly after the surgery. By contrast, warfarin and phenprocoumon are often paused up to a week before surgery, and low-molecular-weight heparins are used to "bridge" the therapy gap, typically for several ...

  3. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  4. Can Taking Antidepressants Cause Weight Loss? - AOL

    www.aol.com/taking-antidepressants-cause-weight...

    One theory to explain antidepressant-related weight gain is that psychotropic medications such as antidepressants can affect neurotransmitters involved in eating behavior, causing an increase in ...

  5. 4 of the Top Prescription Weight Loss Pills & How They Work - AOL

    www.aol.com/4-top-prescription-weight-loss...

    Regular physical activity can help accelerate weight loss, improve metabolism and enhance the benefits of weight loss pills. Aim for 150 minutes per week (or about a half-hour five days a week).

  6. Can Lexapro Cause Weight Loss? What to Know - AOL

    www.aol.com/lexapro-cause-weight-loss-know...

    The researchers found that while nortriptyline was associated with moderate weight gain over a period of six months, the people who were treated with escitalopram only gained 0.14kg (under a third ...

  7. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  8. Anti-obesity medication - Wikipedia

    en.wikipedia.org/wiki/Anti-obesity_medication

    The United States Food and Drug Administration and the European Medicines Agency have approved weight loss medications for adults with either a body-mass index (BMI) of at least 30, or a body-mass index of at least 27 with at least one weight-related comorbidity. This patient population is considered to have sufficiently high baseline health ...

  9. Body roundness index - Wikipedia

    en.wikipedia.org/wiki/Body_roundness_index

    Compared to traditional metrics, such as the body mass index (BMI), (which uses weight and height), BRI may improve predictions of the amount of body fat and the volume of visceral adipose tissue. Despite its common use, BMI can misclassify individuals as obese because it does not distinguish between a person's lean body mass and fat mass.