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Some common genetic causes include mutations in the tyrosinase gene or OCA2 gene. [3] [4] As melanin pigments tend to be in the skin, eye, and hair, these are the commonly affected areas in those with hypopigmentation. [2] Hypopigmentation is common and approximately one in twenty have at least one hypopigmented macule.
Melanosomes, which are organelles containing melanin, must be transported and increased during hyperpigmentation and tanning, while they shrink during hypopigmentation. [4] Skin pigmentation is frequently caused by sun exposure. To protect itself against UV radiation from the sun, the body makes more melanin. As a result, the skin may become ...
Poikiloderma is a skin condition that consists of areas of hypopigmentation, hyperpigmentation, telangiectasias and atrophy. Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage. [1]
telangiectasias, [1] purpura, striae, hypopigmentation [2] Complications: Possible HPA axis involvement [2] Usual onset: within the first 7 days of daily superpotent TCS application under occlusion, within 2 weeks of daily use of less potent TCS or superpotent TCS without occlusion. [2] Causes: Changes in gene regulation and transcription of ...
Hyperpigmentation is excess coloration, or darkening of the skin, [8] while hypopigmentation is a diminished or pallid coloring to the skin. Pigmentation changes in PVA, apparent in the epidermal (outermost) skin layer, may be attributed to incontinence (leaking out) of melanin from melanocytes into the dermal skin layer below. [ 5 ]
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Postinflammatory hypopigmentation is a highly prevalent pigmentary disease. It can happen to any type of skin. Nonetheless, individuals with darker skin seem to have it more frequently and visibly, perhaps due to the color contrast with their natural skin. The incidence of postinflammatory hypopigmentation is the same for both sexes. [2]
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 March 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...