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Frequency. 1 in 1,000,000. Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms, resulting in postural deformities.
Rheumatology. Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS3PE) is a rare syndrome identified by symmetric polyarthritis, synovitis, acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor. [2] If no underlying disorder can be identified (idiopathic RS3PE ...
Eosinophilic fasciitis (/ ˌ iː ə ˌ s ɪ n ə ˈ f ɪ l ɪ k ˌ f æ ʃ i ˈ aɪ t ɪ s, ˌ iː oʊ-,-ˌ f æ s i-/ [2] [3]), also known as Shulman's syndrome, [4] is an inflammatory disease that affects the fascia, other connective tissues, surrounding muscles, blood vessels and nerves.
The Mayo Clinic describes Stiff Person Syndrome as "a rare disorder of motor function characterized by involuntary stiffness of axial muscles and superimposed painful muscle spasms, which are ...
Complex regional pain syndrome is uncommon, and its cause is not clearly understood. CRPS typically develops after an injury, surgery, heart attack, or stroke. [ 8 ][ 12 ] Investigators estimate that 2–5% of those with peripheral nerve injury, [ 13 ] and 13–70% of those with hemiplegia (paralysis of one side of the body) [ 14 ] will develop ...
Mayo Clinic. Research. Hyperthyroidism. Henry Stanley Plummer (March 3, 1874 – December 31, 1936) was an American internist and endocrinologist. He, along with William Mayo, Charles Mayo, Augustus Stinchfield, E. Starr Judd, Christopher Graham, and Donald Balfour founded Mayo Clinic. Plummer is honored by the Plummer Building, which still ...
Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder. The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles (myotonia) and rigidity. [1]
Hypermobility spectrum disorder (HSD), related to earlier diagnoses such as hypermobility syndrome (HMS), and joint hypermobility syndrome (JHS) is a heritable connective tissue disorder [3] that affects joints and ligaments. Different forms and sub-types have been distinguished, but it does not include asymptomatic joint hypermobility ...