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Aldehyde dehydrogenase is a polymorphic enzyme [3] responsible for the oxidation of aldehydes to carboxylic acids. [3] There are three different classes of these enzymes in mammals: class 1 (low K m, cytosolic), class 2 (low K m, mitochondrial), and class 3 (high K m, such as those expressed in tumors, stomach, and cornea).
In enzymology, an aldehyde dehydrogenase (FAD-independent) (EC 1.2.99.7) is an enzyme that catalyzes the chemical reaction. an aldehyde + H 2 O + acceptor a carboxylate + reduced acceptor. The 3 substrates of this enzyme are aldehyde, H 2 O, and acceptor, whereas its two products are carboxylate and reduced acceptor.
In enzymology, an aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) is an enzyme that catalyzes the chemical reaction. an aldehyde + NAD + + H 2 O an acid + NADH + H +. The 3 substrates of this enzyme are aldehyde, NAD +, and H 2 O, whereas its 3 products are acid, NADH, and H +.
Aldehyde dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the ALDH2 gene located on chromosome 12. [ 5 ] [ 6 ] ALDH2 belongs to the aldehyde dehydrogenase family of enzymes. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.
Aldehyde dehydrogenase, dimeric NADP-preferring is an enzyme that in humans is encoded by the ALDH3A1 gene. [ 5 ] [ 6 ] [ 7 ] Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids.
The systematic name of this enzyme class is aldehyde:NAD(P)+ oxidoreductase. Other names in common use include aldehyde dehydrogenase [NAD(P)+] , and ALDH . This enzyme participates in 5 metabolic pathways : glycolysis / gluconeogenesis , histidine metabolism , tyrosine metabolism , phenylalanine metabolism , and metabolism of xenobiotics by ...
Aldehyde dehydrogenase isozymes are NAD(P)-dependent dehydrogenases that catalyze the oxidation of an aldehyde into the corresponding carboxylic acid while reducing NAD+ or NADP+. ALDH1A1 is the only ALDH1 isozyme known to oxidize 9-cis retinaldehyde into 9-cis retinoic acid [ 7 ] and thus serve as the only known activator of the rexinoid ...
72535 Ensembl ENSG00000137124 ENSMUSG00000035561 UniProt P30837 Q9CZS1 RefSeq (mRNA) NM_000692 NM_028270 RefSeq (protein) NP_000683 NP_082546 Location (UCSC) Chr 9: 38.39 – 38.4 Mb Chr 4: 45.8 – 45.8 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene. Function This protein belongs to ...