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Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe pain. [7] Typically, long-term use is only recommended for pain due to cancer. [9]
Codeine is used to treat mild to moderate pain. [4] It is commonly used to treat post-surgical dental pain. [13]Weak evidence indicates that it is useful in cancer pain, but it may have increased adverse effects, especially constipation, compared to other opioids. [14]
As is typical of opioids, common side effects include constipation, itchiness, and nausea. [10] Serious side effects may include hallucinations, seizures, increased risk of serotonin syndrome, decreased alertness, and drug addiction. [10] A change in dosage may be recommended in those with kidney or liver problems. [10]
In older adults, opioid use is associated with increased adverse effects such as "sedation, nausea, vomiting, constipation, urinary retention, and falls". [66] As a result, older adults taking opioids are at greater risk for injury. [67] Opioids do not cause any specific organ toxicity, unlike many other drugs, such as aspirin and
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
Laxatives are designed for constipation, not weight loss, and can lead to serious side effects and dangerous complications when used incorrectly. When you lose weight on laxatives, it's from water ...
Metamizole has a potential of blood-related toxicity (blood dyscrasias), but causes less kidney, cardiovascular, and gastrointestinal toxicity than non-steroidal anti-inflammatory drugs (NSAIDs). [11] Like NSAIDs, it can trigger bronchospasm or anaphylaxis, especially in those with asthma. [14]
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