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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
Phage injecting its genome into bacterial cell An electron micrograph of bacteriophages attached to a bacterial cell. These viruses are the size and shape of coliphage T1. Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections.
During the lysogenic cycle, the virus genome is incorporated as prophage and a repressor prevents viral replication. Nonetheless, a temperate phage can escape repression to replicate, produce viral particles, and lyse the bacteria. [13] The temperate phage escaping repression would be a disadvantage for the bacteria.
Phage typing is based on the specific binding of phages to antigens and receptors on the surface of bacteria and the resulting bacterial lysis or lack thereof. [4] The binding process is known as adsorption. [5] Once a phage adsorbs to the surface of a bacteria, it may undergo either the lytic cycle or the lysogenic cycle. [6]
A prophage is a bacteriophage (often shortened to "phage") genome that is integrated into the circular bacterial chromosome or exists as an extrachromosomal plasmid within the bacterial cell. [1] Integration of prophages into the bacterial host is the characteristic step of the lysogenic cycle of temperate phages.
Vampire viruses prey on other viruses to replicate themselves. These particular viruses are caused when a bacteriophage latches onto a soil-based virus’s neck and uses its “life” to survive ...
Biosynthesis – the phage DNA replicates inside the cell, synthesizing new phage DNA and proteins; Maturation – the replicated material assembles into fully formed viral phages (each made up of a head, a tail and tail fibers) Lysis - cell wall or membrane ruptures, disintegrating it and releasing the virus in the process
Several bacteriophages contain toxin genes that become incorporated into the host bacteria genome through infection and render the bacteria toxic. [9] Many well known bacterial toxins are produced from specific strains of the bacteria species that have obtained toxigenicity through lysogenic conversion, pseudolysogeny, or horizontal gene ...