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Microangiopathy (also known as microvascular disease, small vessel disease (SVD) or microvascular dysfunction) is a disease of the microvessels, small blood vessels in the microcirculation. [1] It can be contrasted to macroangiopathies such as atherosclerosis , where large and medium-sized arteries (e.g., aorta , carotid and coronary arteries ...
Named after the Dutch mathematician Bartel Leendert van der Waerden, the Van der Waerden test is a statistical test that k population distribution functions are equal. The Van der Waerden test converts the ranks from a standard Kruskal-Wallis test to quantiles of the standard normal distribution (details given below).
There are two types of angiopathy: macroangiopathy and microangiopathy. [2] In macroangiopathy, atherosclerosis and a resultant blood clot forms on the large blood vessels, sticks to the vessel walls, and blocks the flow of blood. Macroangiopathy in the heart is coronary artery disease; in the brain, it is cerebrovascular disease.
In diseases such as hemolytic uremic syndrome, disseminated intravascular coagulation, thrombotic thrombocytopenic purpura, and malignant hypertension, the endothelial layer of small vessels is damaged with resulting fibrin deposition and platelet aggregation.
The term normal score is used with two different meanings in statistics. One of them relates to creating a single value which can be treated as if it had arisen from a standard normal distribution (zero mean, unit variance). The second one relates to assigning alternative values to data points within a dataset, with the broad intention of ...
Damage to small blood arteries is the cause of what called microangiopathy, which may lead to any of these: Diabetic retinopathy , caused by alterations in retinal microcirculation, leading to the growth of friable and poor-quality new blood vessels in the retina or capillary closure which causes ischemia or extravasation of intravascular ...
Thrombotic microangiopathy (TMA) is a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury. [1] It may be seen in association with thrombocytopenia , anemia , purpura and kidney failure .
Diabetic angiopathy is a form of angiopathy associated with diabetic complications. [1] While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical.