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The importance of correctly recognizing progressive muscular atrophy as opposed to ALS is important for several reasons. The prognosis is a little better. A recent study found the 5-year survival rate in PMA to be 33% (vs 20% in ALS) and the 10-year survival rate to be 12% (vs 6% in ALS). [1]
Progressive disease or progressive illness is a disease or physical ailment whose course in most cases is the worsening, growth, or spread of the disease. This may happen until death, serious debility, or organ failure occurs. [1] Some progressive diseases can be halted and reversed by treatment (surgical, dietary, or lifestyle interventions).
These injuries lead to an increase in morbidity and a greater likelihood that they will be admitted to a nursing home. [48] Approximately 95 percent of all hip fractures reported are due to an unforeseen fall and 25-75 percent of those do not recover fully to the mobility they had prior to the fall. [49]
If the injury is below cervical vertebrae C5, the patient will exhibit diaphragmatic breathing due to loss of nervous control of the intercostal muscles (which are required for thoracic breathing). If the injury is above C3, the patient will go into respiratory arrest immediately following the injury, due to loss of nervous control of the ...
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A Norwegian study of more than 2.5 million people published in March 2009 has found an HSP prevalence rate of 7.4/100,000 of population – a higher rate, but in the same range as previous studies. No differences in rate relating to gender were found, and average age at onset was 24 years. [ 33 ]
The acronym RIFLE is used to define the spectrum of progressive kidney injury seen in AKI: [14] [15] Pathophysiology of acute kidney injury in the proximal renal tubule. Risk: 1.5-fold increase in the serum creatinine, or glomerular filtration rate (GFR) decrease by 25 percent, or urine output <0.5 mL/kg per hour for six hours.
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