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The stages of squamous cell carcinoma range from 0–4. Stage 0 is a precancerous stage, and stage 4 is advanced or metastatic cancer.
The 5-year survival is 99 percent when detected early. Once SCC has spread to the lymph nodes and beyond, the survival rates are lower. Yet this cancer is still treatable with surgery and...
The prognosis for cutaneous SSC after definitive treatment is generally good, with three-year disease-specific survival of around 85% [5]. Metastasis of cutaneous squamous cell carcinoma (cSCC) is rare. However, certain tumor and patient characteristics increase the risk of metastasis.
Key Points. Metastatic squamous neck cancer with occult primary is a disease in which squamous cell cancer spreads to lymph nodes in the neck and it is not known where the cancer first formed in the body. Signs and symptoms of metastatic squamous neck cancer with occult primary include a lump or pain in the neck or throat.
Because of this, signs of metastasis may include a painful or tender lump in the neck or a sore throat that doesn’t improve or go away. How is metastatic squamous cell carcinoma treated?
SCC metastasis is generally associated with a poor prognosis with a 3-year disease-free survival rate in adult patients of 56% . Relapse of SCC is common, with the cumulative relapse rate ~29% within 1-year of treatment.
Staging of cutaneous squamous-cell carcinoma has changed dramatically in the past 10 years, with several refinements integrating clinical and pathological risk factors for local recurrence...