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  2. History of neuraxial anesthesia - Wikipedia

    en.wikipedia.org/wiki/History_of_neuraxial...

    "Anesthesia of nerve roots with cocaine". Cleveland Medical Journal. 2: 355. Cushing, HW (1902). "I. On the Avoidance of Shock in Major Amputations by Cocainization of Large Nerve-Trunks Preliminary to their Division. With Observations on Blood-Pressure Changes in Surgical Cases". Annals of Surgery. 36 (3): 321– 45. doi:10.1097/00000658 ...

  3. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    Topical cocaine is sometimes used as a local numbing agent and vasoconstrictor to help control pain and bleeding with surgery of the nose, mouth, throat or lacrimal duct. It is also used for topical airway anaesthesia for procedures such as awake fibreoptic bronchoscopy or intubation.

  4. Cocaine-induced midline destructive lesions - Wikipedia

    en.wikipedia.org/wiki/Cocaine-Induced_Midline...

    The only reliable treatment of CIMDL is cessation of cocaine abuse, which is considered a necessary prerequisite for surgical reconstruction. If abstention can be achieved, reconstructive surgery, prosthetics and medical therapy can achieve satisfactory results.

  5. William Stewart Halsted - Wikipedia

    en.wikipedia.org/wiki/William_Stewart_Halsted

    William Stewart Halsted, M.D. (September 23, 1852 – September 7, 1922) was an American surgeon who emphasized strict aseptic technique during surgical procedures, was an early champion of newly discovered anesthetics, and introduced several new operations, including the radical mastectomy for breast cancer.

  6. Karl Koller (ophthalmologist) - Wikipedia

    en.wikipedia.org/wiki/Karl_Koller_(ophthalmologist)

    Koller introduced cocaine as a local anaesthetic for eye surgery. Prior to this discovery, he had tested solutions such as chloral hydrate and morphine as anaesthetics in the eyes of laboratory animals without success. Freud was fully aware of the pain-killing properties of cocaine, but Koller recognized its tissue-numbing capabilities, and in ...

  7. Kaley Cuoco reveals past addiction that led to major surgery

    www.aol.com/entertainment/2015-01-14-kaley-cuoco...

    Kaley Cuoco went on "The Ellen Degeneres Show" and revealed a past addiction that ultimately led to some serious surgery. Cuoco went under the knife over the holidays for her sinuses and told ...

  8. Anesthesia for eye surgery - Wikipedia

    en.wikipedia.org/wiki/Anesthesia_for_eye_surgery

    Inhalational anaesthesia was used for this purpose. [citation needed] Egyptian surgeons used carotid compression to produce transient ischemia during eye surgery to reduce the perception of pain. [citation needed] In 1884, Karl Koller used cocaine for ocular surgery. [citation needed] The same year, Herman Knapp used cocaine for retrobulbar block.

  9. Spinal anaesthesia - Wikipedia

    en.wikipedia.org/wiki/Spinal_anaesthesia

    The first planned spinal anaesthesia for surgery on a human was administered by August Bier (1861–1949) on 16 August 1898, in Kiel, when he injected 3 ml of 0.5% cocaine solution into a 34-year-old labourer. [14] After using it on six patients, he and his assistant each injected cocaine into the other's spine. They recommended it for ...