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While use during pregnancy is not recommended, risk appears to be low. [6] The use of other medications in this class appear to be safe while breastfeeding; however, the safety of levofloxacin is unclear. [6] Levofloxacin was patented in 1985 and approved for medical use in the United States in 1996.
[6] [7] Current evidence suggests that first line treatment with β 2 agonists, calcium channel blockers, or NSAIDs to prolong pregnancy for up to 48 hours is the best course of action to allow time for glucocorticoid administration. [1] Various types of agents are used, with varying success rates and side effects.
The Mercer protocol is a common regimen for antibiotic prophylaxis in the context of preterm premature rupture of membranes (PPROM) during pregnancy, when immediate delivery is contraindicated due to known or suspected fetal lung immaturity.
Safety concerns exist for fluoroquinolone use during pregnancy, so they are contraindicated unless no other safe alternative antibiotic exists. [54] However, one meta-analysis looking at the outcome of pregnancies involving quinolone use in the first trimester found no increased risk of malformations. [ 55 ]
Enoxaparin is listed as Pregnancy Category B, meaning animal studies have failed to show harmful effects to the fetus and therefore are safe to use in pregnant women. [ 37 ] [ 39 ] However, pregnant women taking LMWH may not experience the full anticoagulant effect due to the nature of the medication compared to other anticoagulants (i.e ...
Common side effects include low blood sugar, while more serious side effects may include low blood potassium. [21] It is generally considered safe for use during pregnancy and breastfeeding. [23] It functions similarly to human insulin by increasing glucose uptake in tissues and reducing the amount of glucose produced by the liver in ...
Selective reduction of twins was very controversial at first but has gradually become more accepted. One of the authors of the 1988 guidelines updated his stance and expressed a desire for the procedure to become more available in 2014. Sex-selective reduction is widely considered to be unethical in making decisions about which fetus to keep ...
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy.It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk.