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Difference between Z-test and t-test: Z-test is used when sample size is large (n>50), or the population variance is known. t-test is used when sample size is small (n<50) and population variance is unknown. There is no universal constant at which the sample size is generally considered large enough to justify use of the plug-in test.
The Z-factor defines a characteristic parameter of the capability of hit identification for each given assay. The following categorization of HTS assay quality by the value of the Z-Factor is a modification of Table 1 shown in Zhang et al. (1999); [2] note that the Z-factor cannot exceed one.
Suppose we are using a Z-test to analyze the data, where the variances of the pre-treatment and post-treatment data σ 1 2 and σ 2 2 are known (the situation with a t-test is similar). The unpaired Z-test statistic is ¯ ¯ / + /, The power of the unpaired, one-sided test carried out at level α = 0.05 can be calculated as follows:
The table shown on the right can be used in a two-sample t-test to estimate the sample sizes of an experimental group and a control group that are of equal size, that is, the total number of individuals in the trial is twice that of the number given, and the desired significance level is 0.05. [4]
Comparison of the various grading methods in a normal distribution, including: standard deviations, cumulative percentages, percentile equivalents, z-scores, T-scores. In statistics, the standard score is the number of standard deviations by which the value of a raw score (i.e., an observed value or data point) is above or below the mean value of what is being observed or measured.
Example: Prob(Z ≤ 0.69) = 0.7549. Complementary cumulative gives a probability that a statistic is greater than Z. This equates to the area of the distribution above Z. Example: Find Prob(Z ≥ 0.69). Since this is the portion of the area above Z, the proportion that is greater than Z is found by subtracting Z from 1.
Z and V are independent; A different distribution is defined as that of the random variable defined, for a given constant μ, by (+). This random variable has a noncentral t-distribution with noncentrality parameter μ. This distribution is important in studies of the power of Student's t-test.
Test statistic is a quantity derived from the sample for statistical hypothesis testing. [1] A hypothesis test is typically specified in terms of a test statistic, considered as a numerical summary of a data-set that reduces the data to one value that can be used to perform the hypothesis test.