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The safety profile of 7-keto-DHEA appears to be generally well-tolerated with a low side-effect profile, but changes in blood hormone parameters have been reported. Given these uncertainties, the potential benefits and safety of 7-keto-DHEA, particularly with long-term use, are not established.
In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56] As DHEA-S can be converted back into DHEA, it serves as a circulating reservoir for DHEA, thereby extending the duration of DHEA. [57] [20] Metabolites of DHEA include DHEA-S, 7α-hydroxy-DHEA, 7β-hydroxy-DHEA, 7-keto-DHEA, 7α-hydroxyepiandrosterone, and 7β ...
• Lardy has demonstrated that 7-Keto DHEA is around 2.5 times more powerful, milligramme for milligramme, than DHEA, and this with no side effects. In fact, 7-Keto DHEA, metabolized in the body from DHEA, may be responsible for most of the beneficial effects attributed to DHEA. 7-Keto DHEA is more effective than DHEA for improving memory ...
What are the possible side effects of taking expired vitamins? “There isn’t a promise that the vitamin will pack a full punch if you take it after the expiration date, but there aren’t any ...
The DHEA content in the daily recommended dose of Dexatrim Max ranges from 100–200 mg per day. [1] Side effects at this dose can include acne, hair loss, facial hair growth and deeper voice in women, stomach upset, and high blood pressure, particularly if the supplement is used for a longer period of time. [11]
DHEA and DHEA-S are the most abundant circulating steroids in the body. [29] Plasma levels of DHEA-S are 100 or more times higher than those of DHEA, 5 to 10 times higher than those of cortisol, 100 to 500 times those of testosterone, and 1,000 to 10,000 times higher than those of estradiol. [30] [3] Levels of DHEA and DHEA-S vary throughout life.
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