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Mycobacterium ulcerans is a species of bacteria found in various aquatic environments. The bacteria can infect humans and some other animals, causing persistent open wounds called Buruli ulcer . M. ulcerans is closely related to Mycobacterium marinum , from which it evolved around one million years ago, and more distantly to the mycobacteria ...
M. ulcerans is a mycobacterium, closely related to Mycobacterium marinum which infects aquatic animals and, rarely, humans. [9] It is more distantly related to other slow-growing mycobacteria that infect humans, such as Mycobacterium tuberculosis , which causes tuberculosis , and Mycobacterium leprae , which causes leprosy . [ 10 ]
This instrument is produced by Becton Dickinson (BD). It is specially designed to accommodate Mycobacteria Growth Indicator Tube (MGIT) and incubate them at 37 °C. The instrument scans the MGIT every 60 minutes for increased fluorescence.
Runyon III organisms (nonchromogens) are slow-growing and never produce pigment, regardless of culture conditions. The group includes Mycobacterium avium and Mycobacterium intracellulare (together known as the MAC complex), Mycobacterium ulcerans and numerous other organisms. Mycobacterium xenopi is also a nonchromogen.
Mycobacteria are a family of small, rod-shaped bacilli that can be classified into three main groups for diagnosis and treatment: Mycobacterium tuberculosis complex, which can cause tuberculosis: M. tuberculosis, M. bovis, M. africanum, M. microti and M. canettii; M. leprae and M. lepromatosis, which cause Hansen's disease, also called leprosy
There is now considerable evidence to suggest that this disease is an infection. Mycobacterium ulcerans has recently been isolated from lesions and is unique to tropical ulcers. [5] Early lesions may be colonized or infected by, Bacillus fusiformis (Vincent's organism), anaerobes and spirochaetes.
Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenic mycobacteria species including M. ulcerans, M. liflandii (an unofficial designation), M. pseudoshottsii, and some strains of M. marinum. These mycobacteria are collectively referred to as mycolactone-producing mycobacteria or MPM ...
In January 2024, a publication by an Australian research group demonstrated significant genetic similarity between Mycobacterium ulcerans in humans and possums, compared to PCR screening of M. ulcerans from trapped Aedes notoscriptus mosquitoes, and concluded that Mycobacterium ulcerans, the causative pathogen of Buruli ulcer, is transmitted by mosquitos.