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4128 17161 Ensembl ENSG00000189221 ENSMUSG00000025037 UniProt P21397 Q64133 RefSeq (mRNA) NM_001270458 NM_000240 NM_173740 RefSeq (protein) NP_000231 NP_001257387 NP_776101 Location (UCSC) Chr X: 43.65 – 43.75 Mb Chr X: 16.49 – 16.55 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse MAOA gene is located on the short (p) arm of the X chromosome at position 11.3. Monoamine oxidase A ...
Rare mutations in the gene are associated with Brunner syndrome. [medical citation needed] A study based on the Dunedin cohort concluded that maltreated children with a low-activity polymorphism in the promoter region of the MAO-A gene were more likely to develop antisocial conduct disorders than maltreated children with the high-activity ...
English: A section of chromosome X, showing the relative positions of MAOA and MAOB genes and mutations typed in [1]. Mutations that were polymorphic in the Maori group are coloured blue. The labels for each mutation refer to the segment, region, and nucleotide position from [2].
Brunner syndrome is a rare genetic disorder associated with a mutation in the MAOA gene. It is characterized by lower than average IQ (typically about 85), problematic impulsive behavior (such as pyromania, hypersexuality and violence), sleep disorders and mood swings. [1] [2] It was identified in fourteen males from one family in 1993.
Gene therapy has allowed several children born with inherited deafness to hear. On Tuesday, the Children's Hospital of Philadelphia announced similar improvements in an 11-year-old boy treated there.
They are deactivated in the body by the enzymes known as monoamine oxidases which clip off the amine group. Monoaminergic systems, i.e., the networks of neurons that use monoamine neurotransmitters, are involved in the regulation of processes such as emotion, arousal, and certain types of memory.
The DRD2 Gene results in humans finding seemingly rewarding paths such as drug abuse. Through studies, DRD2 seems to be a risk factor in delinquency when children have related family trauma events. [19] DAT1 is a gene that regulates dopamine levels in the brain.
Human protein-coding gene pages: •Python code for maintaining the list •List of human protein-coding genes page 1 covers genes A1BG–EPGN •List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7