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4128 17161 Ensembl ENSG00000189221 ENSMUSG00000025037 UniProt P21397 Q64133 RefSeq (mRNA) NM_001270458 NM_000240 NM_173740 RefSeq (protein) NP_000231 NP_001257387 NP_776101 Location (UCSC) Chr X: 43.65 – 43.75 Mb Chr X: 16.49 – 16.55 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse MAOA gene is located on the short (p) arm of the X chromosome at position 11.3. Monoamine oxidase A ...
Monoamine oxidases (MAO) (EC 1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. [1] [2] They are found bound to the outer membrane of mitochondria in most cell types of the body.
English: A section of chromosome X, showing the relative positions of MAOA and MAOB genes and mutations typed in [1]. Mutations that were polymorphic in the Maori group are coloured blue. The labels for each mutation refer to the segment, region, and nucleotide position from [2].
Brunner syndrome is a rare genetic disorder associated with a mutation in the MAOA gene. It is characterized by lower than average IQ (typically about 85), problematic impulsive behavior (such as pyromania, hypersexuality and violence), sleep disorders and mood swings. [1] [2] It was identified in fourteen males from one family in 1993.
A phylogenetic tree showing how a number of monoamine receptors are related to each other. Monoamine neurotransmitter systems occur in virtually all vertebrates, where the evolvability of these systems has served to promote the adaptability of vertebrate species to different environments. [12] [13]
There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.
4129 109731 Ensembl ENSG00000069535 ENSMUSG00000040147 UniProt P27338 Q8BW75 RefSeq (mRNA) NM_000898 NM_172778 RefSeq (protein) NP_000889 NP_766366 Location (UCSC) Chr X: 43.77 – 43.88 Mb Chr X: 16.58 – 16.68 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Monoamine oxidase B (MAO-B) is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs ...
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines.