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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
The National Hip Fracture Database (NHFD) is a nationwide audit within the NHS concerning the management and outcomes of patients with hip fractures.. It was initially set up by the British Orthopaedic Association and the British Geriatrics Society, however it is now commissioned by the Healthcare Quality Improvement Partnership (HQIP), a consortium of the Academy of Medical Royal Colleges and ...
Fractures of the diaphysis, or middle of the femur, are managed differently from those at the head, neck, and trochanter; those are conventionally called hip fractures (because they involve the hip joint region). Thus, mentions of femoral fracture in medicine usually refer implicitly to femoral fractures at the shaft or distally.
Hip fractures are very dangerous episodes, especially for elderly and frail patients. The risk of dying from the stress of the surgery and the injury in the first thirty days is about 7%. [53] At one year after fracture, this may reach 30%. [54] If the condition is untreated the pain and immobility imposed on the patient increase that risk.
Hip fractures are responsible for the most serious consequences of osteoporosis. In the United States, more than 250,000 hip fractures annually are attributable to osteoporosis. [192] A 50-year-old white woman is estimated to have a 17.5% lifetime risk of fracture of the proximal femur. The incidence of hip fractures increases each decade from ...
Pelvic fractures make up around 3% of adult fractures. [1] Stable fractures generally have a good outcome. [1] The risk of death with an unstable fracture is about 15%, while those who also have low blood pressure have a risk of death approaching 50%. [2] [4] Unstable fractures are often associated with injuries to other parts of the body. [3]
Fragility fractures of the spine are most commonly described, but the condition can be associated with other types of fracture. [ 1 ] [ 2 ] The symptoms usually appear during or after a first pregnancy with the most common complaint being severe back pain [ 3 ]
The enlarging uterus, growing fetus, placenta, amniotic fluid, normal increase in body fat, and increase in water retention all contribute weight gain during pregnancy. The amount of weight gain can vary from 5 pounds (2.3 kg) to over 100 pounds (45 kg). In the United States, the range of weight gain that doctors generally recommend is 25 ...