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It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine). [4] [5] The paramagnetic property of gadoteric acid reduces the T1 relaxation time (and to some extent the T2 and T2* relaxation times) in MRI, which is the source of its clinical utility. Because ...
The World Health Organization issued a restriction on use of several gadolinium contrast agents in November 2009 stating that "High-risk gadolinium-containing contrast agents (Optimark, Omniscan, Magnevist, Magnegita, and Gado-MRT ratiopharm) are contraindicated in patients with severe kidney problems, in patients who are scheduled for or have ...
In the form of the methylglucamine salt meglumine gadobenate or gadobenate dimeglumine , it is used as a gadolinium-based MRI contrast medium. [4] BOPTA is a derivative of DTPA in which one terminal carboxyl group, –C(O)OH is replaced by -C–O–CH 2 C 6 H 5. Thus gadobenic acid is closely related to gadopentetic acid.
Gadopentetic acid, sold under the brand name Magnevist, is a gadolinium-based MRI contrast agent. [2]It is usually administered as a salt of a complex of gadolinium with DTPA (diethylenetriaminepentacetate) with the chemical formula A 2 [Gd(DTPA)(H 2 O)]; when cation A is the protonated form of the amino sugar meglumine the salt goes under the name "gadopentetate dimeglumine".
Sloan's Liniment, right, was once a popular over-the-counter drug. Liniment (from Latin: linere, meaning "to anoint"), also called embrocation and heat rub, is a medicated topical preparation for application to the skin.
February 5, 2025 at 2:03 AM. ... For instance, Gatorade G2 (which is Gatorade’s lower-calorie cousin) contains only 40 calories in a 16 fluid ounce bottle, per Healthline.
Meglumine is a sugar alcohol derived from glucose that contains an amino group modification. It is often used as an excipient in pharmaceuticals [ 1 ] and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine , iothalamate meglumine , and iodipamide meglumine .
A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluids within the body in medical imaging. [1] Contrast agents absorb or alter external electromagnetism or ultrasound, which is different from radiopharmaceuticals, which emit radiation themselves.