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Hypopnea during sleep is classed as a sleep disorder. With moderate to severe hypopnea, sleep is disturbed such that patients may get a full night's sleep but still not feel rested. The disruption in breathing causes a drop in blood oxygen level, which may in turn disrupt the stages of sleep.
The conditions of hypoxia and hypercapnia, whether caused by apnea or not, trigger additional effects on the body.The immediate effects of central sleep apnea on the body depend on how long the failure to breathe endures, how short is the interval between failures to breathe, and the presence or absence of independent conditions whose effects amplify those of an apneic episode.
In adults with coronary artery disease, a severe drop in blood oxygen level can cause angina, arrhythmias, or heart attacks (myocardial infarction). Longstanding recurrent episodes of apnea, over months and years, may cause an increase in carbon dioxide levels that can change the pH of the blood enough to cause a respiratory acidosis.
Key to understanding whether the lung is involved in a particular case of hypoxemia is the difference between the alveolar and the arterial oxygen levels; this A-a difference is often called the A-a gradient and is normally small. The arterial oxygen partial pressure is obtained directly from an arterial blood gas determination. The oxygen ...
In COVID-19, the arterial and general tissue oxygen levels can drop without any initial warning.The chest x-ray may show diffuse pneumonia.Cases of silent hypoxia with COVID-19 have been reported for patients who did not experience shortness of breath or coughing until their oxygen levels had depressed to such a degree that they were at risk of acute respiratory distress (ARDS) and organ failure.
Without treatment, the sleep deprivation and lack of oxygen caused by sleep apnea increases health risks such as cardiovascular disease, aortic disease (e.g. aortic aneurysm), [165] high blood pressure, [166] [167] stroke, [168] diabetes, clinical depression, [169] weight gain, obesity, [66] and even death.
Central hypoventilation syndrome (CHS) is a sleep-related breathing disorder that causes ineffective breathing, apnea, or respiratory arrest during sleep (and during wakefulness in severe cases). CHS can either be congenital (CCHS) or acquired (ACHS) later in life.
Sleep apnea (or sleep apnoea in British English; /æpˈniːə/) is a sleep disorder characterized by pauses in breathing or instances of shallow or infrequent breathing during sleep. Each pause in breathing, called an apnea, can last for several seconds to several minutes, and may occur 5 to 30 times or more in an hour.