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4-Fluoroephedrine, also known as 4-fluoro-β-hydroxy-N-methylamphetamine, is a substituted phenethylamine, amphetamine, and β-hydroxyamphetamine derivative. [6] [1] It is the 4-fluoro analogue of ephedrine. [6] [1] The synthesis of 4-fluoroephedrine has been described. [7] It can serve as a precursor in the synthesis of 4-fluoromethamphetamine ...
Substituted amphetamines, or simply amphetamines, are a class of compounds based upon the amphetamine structure; [1] it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
Flephedrone, also known as 4-fluoromethcathinone (4-FMC), is a stimulant drug of the cathinone chemical class that has been sold online as a designer drug starting in ...
4-Fluoroamphetamine is a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. [9] The respective EC 50 values are 2.0 x 10 −7 M, 7.3 x 10 −7 M, and 0.37 x 10 −7 M, while the IC 50 values are 7.7 x 10 −7 M, 68 x 10 −7 M, and 4.2 x 10 −7 M. [3]
Some β-hydroxyamphetamines have had their side chain extended and cyclized.Examples include certain substituted phenylmorpholines like phenmetrazine and phendimetrazine and their analogues; substituted phenylmorpholines related to bupropion like radafaxine (cyclized (2S,3S)-hydroxybupropion) and manifaxine; certain substituted aminorexes like 4-methylaminorex and 4,4'-dimethylaminorex; and ...
4-Fluoromethylphenidate was studied further along with other analogues of (±)-threo-methylphenidate (TMP) to assess their potential as anti-cocaine medications. 4F-MPH was reported as having an ED 50 mg/kg of 0.26 (0.18–0.36), regarding its efficacy as a substitute for cocaine, and a relative potency of 3.33 compared to methylphenidate for ...
4'-Fluoro-α-pyrrolidinooctanophenone (also known as 4-Fluoro-PV-9, FPOP and 4-Fluoro-α-POP) is a stimulant drug of the cathinone class which has been reported as a novel designer drug. [ 1 ] [ 2 ] Legality
4'-Fluoro-α-pyrrolidinopentiophenone (also known as O-2370, FPVP and 4-Fluoro-α-PVP) is a stimulant drug of the cathinone class which has been reported as a novel designer drug. [ 1 ] [ 2 ] [ 3 ] Legality