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The psychoactive effects of cannabis, known as a "high", are subjective and vary among persons and the method of use. When THC enters the blood stream and reaches the brain, it binds to cannabinoid receptors. The endogenous ligand of these receptors is anandamide, the effects of which THC emulates.
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
A participant in a study on the effects of cannabis, shows the marijuana flowers he has grown in his backyard, in Longmont, Colorado, U.S., December 19, 2019.
“The latest research about cannabis use indicates that smoking and inhaling cannabis increases concentrations of blood carboxyhemoglobin (carbon monoxide, a poisonous gas), (and) tar (partly ...
The study found that having high blood pressure readings of over 130/80 mm Hg and high cholesterol were key predictors of major adverse heart and brain events in the marijuana users. “We know ...
The time to onset of effects depends strongly on stomach content, but is usually 1 to 2 hours, and may continue for a considerable length of time, whereas the effects of smoking or vaporizing cannabis are almost immediate, lasting a shorter length of time. [10] All of the active constituents enter the body when cannabis is consumed orally.
More and more states are legalizing marijuana for medical and/or recreational use. High blood pressure is a major risk factor for heart attack and stroke. Stage 1 hypertension is defined as a ...
Marijuana use in the United States is three times above the global average, but in line with other Western democracies. Forty-four percent of American 12th graders have tried the drug at least once, and the typical age of first-use is 16, similar to the typical age of first-use for alcohol but lower than the first-use age for other illicit drugs.