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Here, both infectious forms of VACV, mature virion (MV) and enveloped virion (EV), induce their own macropinocytosis by binding to the cell surface and triggering an actin-mediated plasma membrane protrusion that eventually collapses back onto the plasma membrane sealing the attached virion inside a macropinosome, which then goes through a ...
Pinocytosis. In cellular biology, pinocytosis, otherwise known as fluid endocytosis and bulk-phase pinocytosis, is a mode of endocytosis in which small molecules dissolved in extracellular fluid are brought into the cell through an invagination of the cell membrane, resulting in their containment within a small vesicle inside the cell.
[8] Pinocytosis, which usually occurs from highly ruffled regions of the plasma membrane, is the invagination of the cell membrane to form a pocket, which then pinches off into the cell to form a vesicle (0.5–5 μm in diameter) filled with a large volume of extracellular fluid and molecules within it (equivalent to ~100 CCVs). The filling of ...
The Urdu Wikipedia (Urdu: اردو ویکیپیڈیا), started in January 2004, is the Standard Urdu-language edition of Wikipedia, a free, open-content encyclopedia. [1] [2] As of 19 February 2025, it has 217,936 articles, 190,727 registered users and 7,544 files, and it is the 54th largest edition of Wikipedia by article count, and ranks 20th in terms of depth among Wikipedias with over ...
Bleb growth is driven by intracellular pressure (abnormal growth) generated in the cytoplasm when the actin cortex undergoes actomyosin contractions. [5] The disruption of the membrane-actin cortex interactions [4] are dependent on the activity of myosin-ATPase [6] Bleb initiation is affected by three main factors: high intracellular pressure, decreased amounts of cortex-membrane linker ...
Triggering receptor expressed on myeloid cells 2 (TREM2) is a protein that in humans is encoded by the TREM2 gene. [ 5 ] [ 6 ] [ 7 ] TREM2 is expressed on macrophages, immature monocyte-derived dendritic cells , osteoclasts , and microglia , [ 8 ] which are immune cells in the central nervous system . [ 9 ]
19376 Ensembl ENSG00000109113 ENSMUSG00000002059 UniProt Q9BZG1 P0DI83 Q64008 RefSeq (mRNA) NM_001142624 NM_001142625 NM_001144942 NM_001144943 NM_001256276 NM_001256277 NM_001256278 NM_001256281 NM_031934 NM_001159482 NM_033475 RefSeq (protein) NP_001136096 NP_001136097 NP_001138414 NP_001138415 NP_001243205 NP_001243206 NP_001243207 NP_001243210 NP_114140 NP_001243210.1 NP_001152954 NP ...
The normal mean corpuscular volume (abbreviated to MCV on full blood count results, and also known as mean cell volume) is approximately 80–100 fL. When the MCV is <80 fL, the red cells are described as microcytic and when >100 fL, macrocytic (the latter occurs in macrocytic anemia). The MCV is the average red blood cell size.