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  2. Ranitidine - Wikipedia

    en.wikipedia.org/wiki/Ranitidine

    Ranitidine. Ranitidine, previously sold under the brand name Zantac[a] among others, is a medication used to decrease stomach acid production. [12] It was commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. [12]

  3. Cimetidine - Wikipedia

    en.wikipedia.org/wiki/Cimetidine

    Cimetidine is widely distributed throughout all tissues. [7] It is able to cross the blood–brain barrier and can produce effects in the central nervous system (e.g., headaches, dizziness, somnolence). [2] The volume of distribution of cimetidine is 0.8 L/kg in adults and 1.2 to 2.1 L/kg in children. [6]

  4. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

  5. GSK asks to appeal Delaware ruling allowing Zantac cases to ...

    www.aol.com/news/latest-trial-over-zantac-cancer...

    June 10, 2024 at 7:32 PM. By Brendan Pierson. (Reuters) -GSK and other drugmakers on Monday asked a Delaware court for permission to appeal a ruling allowing more than 70,000 lawsuits claiming ...

  6. Drugmakers' appeal to end Zantac cancer lawsuits ... - AOL

    www.aol.com/news/drugmakers-appeal-end-zantac...

    First approved in 1983, Zantac became the world's best-selling medicine in 1988 and one of the first to top $1 billion in annual sales. It was originally marketed by a forerunner of GSK and later ...

  7. First trial over Zantac cancer claims set to begin in Chicago

    www.aol.com/news/first-trial-over-zantac-cancer...

    April 30, 2024 at 6:46 PM. By Brendan Pierson. (Reuters) -The first trial over claims that blockbuster heartburn drug Zantac, once sold by GSK and other companies, causes cancer is set to begin ...

  8. Zantac - Wikipedia

    en.wikipedia.org/wiki/Zantac

    Zantac can refer to either of two different H 2 antagonists used to reduce gastric acid secretion: Ranitidine, prior to its 2020 withdrawal from the market. Famotidine, following the withdrawal of ranitidine. Categories: Disambiguation pages. Drugs developed by GSK plc.

  9. GSK settles two California lawsuits related to heartburn drug ...

    www.aol.com/news/gsk-settles-two-california...

    September 18, 2024 at 9:19 AM. (Reuters) - British drugmaker GSK said on Wednesday it had agreed to settle two lawsuits in California that claimed its discontinued heartburn drug Zantac caused ...

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