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Streptococcus agalactiae is the most common human pathogen belonging to group B of the Lancefield classification of streptococci —hence the name of group B stretococcal (GBS). Infection with GBS can cause serious illness and sometimes death, especially in newborns, the elderly, and people with compromised immune systems.
Binomial name. Streptococcus agalactiae. Lehmann and Neumann, 1896. Streptococcus agalactiae (also known as group B streptococcus or GBS) is a gram-positive coccus (round bacterium) with a tendency to form chains (as reflected by the genus name Streptococcus). It is a beta- hemolytic, catalase -negative, and facultative anaerobe. [1][2]
Lancefield grouping. Lancefield grouping is a system of classification that classifies catalase -negative Gram-positive cocci based on the carbohydrate composition of bacterial antigens found on their cell walls. [1] The system, created by Rebecca Lancefield, was historically used to organize the various members of the family Streptococcaceae ...
Streptococcus dysgalactiae. Streptococcus dysgalactiae is a gram positive, beta-haemolytic, coccal bacterium belonging to the family Streptococcaceae. It is capable of infecting both humans and animals, but is most frequently encountered as a commensal of the alimentary tract, genital tract, or less commonly, as a part of the skin flora.
Streptolysin O is an oxygen-sensitive cytotoxin, secreted by most group A Streptococcus (GAS), and interacts with cholesterol in the membrane of eukaryotic cells (mainly red and white blood cells, macrophages, and platelets), and usually results in beta-hemolysis under the surface of blood agar.
Streptococcus pyogenes is a species of Gram-positive, aerotolerant bacteria in the genus Streptococcus. These bacteria are extracellular, and made up of non-motile and non-sporing cocci (round cells) that tend to link in chains. They are clinically important for humans, as they are an infrequent, but usually pathogenic, part of the skin ...
CAMP test is shown at bottom left. The CAMP test (Christie–Atkins–Munch-Peterson) is a test to identify group B β-hemolytic streptococci (Streptococcus agalactiae) [1][2] based on their formation of a substance, CAMP factor, [3] that enlarges the area of hemolysis formed by the β- hemolysin elaborated from Staphylococcus aureus.
Group B Strep Support was formed in 1996, after the founders' son had a group B Strep infection. [1] Since then it has established a medical panel [2] and set up a board of trustees. [1] The charity has been heavily involved in public consultations on group B Strep prevention, and in 2012 commented on the National Screening Committee's review ...