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Vitamin D 5. sitocalciferol. (made from 7-dehydrositosterol) Several forms (vitamers) of vitamin D exist, with the two major forms being vitamin D 2 or ergocalciferol, and vitamin D 3 or cholecalciferol. [ 1 ] The term 'vitamin D' refers to either D 2 or D 3, or both, and is known collectively as calciferol.
Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1][7][2] One nanogram per millilitre (1 ng/mL) is equivalent to 2.5 nanomoles per litre (2.5 nmol/L). Severe deficiency: <12 ng/mL = <30 nmol/L[2] Deficiency ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
Reference: National Institutes of Health, Office of Dietary Supplements. Most people need about 600 IU per day, but people over the age of 70 need a little more, somewhere around 800 IU to reduce ...
The latest results compare bone fractures in those who took either a high dose — 2,000 international units of the most active form of vitamin D, called D-3 — or dummy pills every day for five ...
Vitamin D and neurological disorders. Hypovitaminosis D is associated with several neuropsychiatric disorders including dementia, Parkinson's disease, multiple sclerosis, epilepsy, and schizophrenia. There are several proposed mechanisms by which hypovitaminosis D may impact these disorders. One of these mechanisms is through neuronal apoptosis ...
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