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Eflornithine. Eflornithine, sold under the brand name Vaniqa among others, is a medication used to treat African trypanosomiasis (sleeping sickness) and excessive hair growth on the face in women. [1][3][4] Specifically it is used for the second stage of sleeping sickness caused by T. b. gambiense and may be used with nifurtimox. [3][5] It is ...
Eflornithine irreversible inhibits ornithine decarboxylase which is an important enzyme involved in hair growth. [5] Elfornithine does not remove hair through epilation or depilation but rather slows hair growths. Some side effects of eflornithine cream include acne, folliculitis, stinging or burning, skin irritation, redness, itching, and ...
A treatment regimen known as nifurtimox-eflornithine combination treatment (NECT) is used in second stage gambiense African trypanosomiasis throughout Africa where the disease is endemic. [4] The regimen involves slow infusion of 400 mg of eflornithine every 12 hours for 7 days combined with 15 mg/kg of nifurtimox orally three times a day for ...
Yet no one knows precisely what causes it, and it has no cure. PCOS is a common reason why women have difficulty getting pregnant or have complications during pregnancy. This condition is also ...
Anterior view of major and minor (lighter color) body hair growth areas in anatomically typical females and males. Hair removal is the deliberate removal of body hair or head hair. This process is also known as epilatio or depilation. Hair is a common feature of the human body, exhibiting considerable variation in thickness and length across ...
Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2][4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] In Chagas disease it is a second-line option to benznidazole. [5] It is given by mouth.
Paromomycin is an antimicrobial used to treat a number of parasitic infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection. [3] It is a first-line treatment for amebiasis or giardiasis during pregnancy. [3] Otherwise, it is generally a second line treatment option. [3]
For Trypanosoma brucei gambiense, eflornithine or fexinidazole is usually preferred. [1] It is effective in about 95% of people. [3] It is given by injection into a vein. [2] Melarsoprol has a high number of side effects. [4] Common side effects include brain dysfunction, numbness, rashes, and kidney and liver problems. [2]
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