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Serrated polyposis syndrome (SPS), previously known as hyperplastic polyposis syndrome, is a disorder characterized by the appearance of serrated polyps in the colon. While serrated polyposis syndrome does not cause symptoms, the condition is associated with a higher risk of colorectal cancer (CRC). The lifelong risk of CRC is between 25 and 40%.
Micronutrient deficiency is defined as the sustained insufficient supply of vitamins and minerals needed for growth and development, as well as to maintain optimal health. Since some of these compounds are considered essentials (we need to obtain them from the diet), micronutrient deficiencies are often the result of an inadequate intake.
For humans, vitamins and dietary minerals are the primary micronutrients. [3] [6] Human micronutrient requirements are in amounts generally less than 100 milligrams per day, whereas macronutrients are required in gram quantities daily. [7] Deficiencies in micronutrient intake commonly result in malnutrition. [3] [8]
Vitamin deficiency is the condition of a long-term lack of a vitamin.When caused by not enough vitamin intake it is classified as a primary deficiency, whereas when due to an underlying disorder such as malabsorption it is called a secondary deficiency.
Experts agree that eating wholesome, healthy meals, reducing calories, and increasing physical activity are the best ways to lose weight and keep it off long-term. Still, many people turn to ...
There is a risk of development of cancer with fundic gland polyposis, [22] but it varies based on the underlying cause of the polyposis. [4] The risk is highest with congenital polyposis syndromes, and is lowest in acquired causes. [4] [23] As a result, it is recommended that patients with multiple fundic polyps have a colonoscopy to evaluate ...
MUTYH-associated polyposis (also known as MYH-associated polyposis) is an autosomal recessive polyposis syndrome. [1] The disorder is caused by mutations in both alleles (genetic copies) of the DNA repair gene, MUTYH. The MUTYH gene encodes a base excision repair protein, which corrects oxidative damage to DNA.
The World Health Organization criteria for diagnosis of juvenile polyposis syndrome are one of either: More than five juvenile polyps in the colon or rectum; or; Juvenile polyps throughout the gastrointestinal tract; or; Any number of juvenile polyps in a person with a family history of juvenile polyposis. [2]