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Cholesterol synthesis appears to occur mostly at night, [140] so statins with short half-lives are usually taken at night to maximize their effect. Studies have shown greater LDL and total cholesterol reductions in the short-acting simvastatin taken at night rather than the morning, [141] [142] but have shown no difference in the long-acting ...
New research finds that millions of people on statins may not need to be taking the drugs. Researchers came to this conclusion after updating the method of assessing an individual’s 10-year risk ...
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
Additionally, several drugs should be avoided, due to the lack of data regarding their safety. [69] Women are often concerned about the safety of antihypertensives and as a result, many do not take their treatment as prescribed.
Statins are a type of medication that help lower low-density lipoprotein (LDL) cholesterol — or “bad” cholesterol — in the body. This helps keep the arteries clear so blood has an easier ...
Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people who take statin medications. [1] However, there are cases of SAAM in patients who have not taken statin medication, and this can be explained by the exposure to natural sources of statin ...
Statin-induced rhabdomyolysis is rare, occurring in less than 0.1% of people who take statins. [66] [67] [68] Statin induced rhabdomyolysis, as with other statin associated muscle symptoms, occurs most commonly in the first year of treatment but can occur at any time during treatment. [66]
Aluminum and magnesium hydroxide antacids should not be taken within two hours of taking rosuvastatin [4] Coadministration of rosuvastatin with eluxadoline may increase the risk of rhabdomyolysis and myopathy [24] Grapefruit juice negatively interacts with several specific drugs in the statin class, but it has little or no effect on ...