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The epidermal differentiation complex (EDC) is a gene complex comprising over fifty genes encoding proteins involved in the terminal differentiation and cornification of keratinocytes, the primary cell type of the epidermis. In humans, the complex is located on a 1.9 Mbp stretch within chromosome 1q21.
During this differentiation process, keratinocytes permanently withdraw from the cell cycle, initiate expression of epidermal differentiation markers, and move suprabasally as they become part of the stratum spinosum, stratum granulosum, and eventually corneocytes in the stratum corneum.
The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling center to ensure proper development of a limb.
Eve Bjørgum Bunting (née Bolton, December 19, 1928 – October 1, 2023), better known as Eve Bunting, was a Northern Irish-born American writer of more than 250 books. Her work covered a broad array of subjects and included fiction and non-fiction books.
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
Pig skin especially shares similar epidermal and dermal thickness ratios to human skin: pig and human skin share similar hair follicle and blood vessel patterns; biochemically the dermal collagen and elastin content is similar in pig and human skin; and pig skin and human skin have similar physical responses to various growth factors. [1] [2]
This process begins when the EM fungus adheres to the root hair from the soil. [13] The fungus then secretes diffusible factors, to which root hairs are highly sensitive, allowing the hyphae to penetrate into the epidermal cells and create a Hartig net in the first layers of the root cortex. [ 13 ]
A germ layer is a primary layer of cells that forms during embryonic development. [1] The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans (animals that are sister taxa to the sponges) produce two or three primary germ layers.