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Y chromosomal infertility is a direct cause of male infertility due to its effects on sperm production, occurring in approximately one in 2000 males. [22] Usually, affected men show no symptoms, although they may have smaller testes.
About 10–15% of human couples are infertile, unable to conceive.In approximately in half of these cases, the underlying cause is related to the male. The underlying causative factors in the male infertility can be attributed to environmental toxins, systemic disorders such as, hypothalamic–pituitary disease, testicular cancers and germ-cell aplasia.
The most common cause of female infertility are ovulation problems, usually manifested by scanty or absent menstrual periods. [7] Male infertility is most commonly due to deficiencies in the semen , and semen quality is used as a surrogate measure of male fecundity .
"The most common thing that causes infertility in men is a condition that's called varicose veins in the scrotum," Goldstein says. That was the issue for Joshua Kaiser of Texas.
20-30% percent of infertility cases are due to male infertility, 20–35% are due to female infertility, and 25-40% are due to combined problems. [13] In 10–20% of cases, no cause is found. [13] The most common cause of female infertility is ovulatory problems, which generally manifest themselves by sparse or absent menstrual periods. [60]
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In the U.S., approximately 12.7% of reproductive age women seek infertility treatment every year. But that statistic excludes men with infertility issues, which is just one of many reasons actual ...
[3] 15-30% of male factor infertility cases can be correlated with genetic abnormalities. [5] One of the most commonly identified genetic abnormalities in male factor infertility are microdeletions on the long arm of the Y chromosome (Yq), specifically at a region known as the azoospermic factor (AZF) region. [3]