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20807 Ensembl ENSG00000112658 ENSMUSG00000015605 UniProt P11831 Q9JM73 RefSeq (mRNA) NM_003131 NM_001292001 NM_020493 RefSeq (protein) NP_001278930 NP_003122 NP_003122.1 NP_065239 Location (UCSC) Chr 6: 43.17 – 43.18 Mb Chr 17: 46.86 – 46.87 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Serum response factor, also known as SRF, is a transcription factor protein. Function Serum ...
The binding of Elk1 to SRF happens due to protein-protein interaction between the B domain of Elk1 and SRF and the protein-DNA interaction via the A domain. [6] The aforementioned proteins are like recipes for a certain signaling output. If one of these ingredients, such as SRF, is missing, then a different output occurs.
Formins regulate the actin and microtubule cytoskeleton [3] [4] and are involved in various cellular functions such as cell polarity, cytokinesis, cell migration and SRF transcriptional activity. [5] Formins are multidomain proteins that interact with diverse signalling molecules and cytoskeletal proteins, although some formins have been ...
To preserve muscle as you lose body fat, she recommends eating one gram (or more) of high-quality protein, which is essential to muscle growth and repair, for every pound of body weight. And ...
The MADS box protein structure is characterized by four domains. At the N terminal end is the highly conserved MADS DNA binding domain . [ 23 ] Next to the MADS domain is the moderately conserved Intervening (I) and Keratin -like (K) domains, which are involved in specific protein-protein interactions . [ 23 ]
While red meat is a rich source of protein, iron and other nutrients, a recent study linked it to an increased risk of dementia — but some doctors are casting doubt on the claim. Researchers ...
(MyPlate.gov is a great resource for guidance on this.) "It's important to make an effort to fit adequate protein, fiber, fruits, veggies, and vitamins and minerals into that limited eating window ...
In a healthy brain, these protein fragments are broken down and eliminated. In Alzheimer's disease, the fragments accumulate to form hard, insoluble plaques which reduce blood flow. Two proteins are involved in this accumulation of amyloid beta: serum response factor or SRF and myocardin. [9]