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Brexpiprazole, sold under the brand name Rexulti among others, is an atypical antipsychotic medication used for the treatment of major depressive disorder, schizophrenia, and agitation associated with dementia due to Alzheimer's disease. [11] [13] [14] The most common side effects include akathisia (a constant urge to move) and weight gain. [12]
There has been a study that suggests antipsychotics are associated with possible cortical reconfiguration and gray matter loss, [19] but correlational data also suggests patients who consume antipsychotics, like people with schizophrenia, tend to engage in unhealthy habits like smoking which may exacerbate gray matter loss.
Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
An assessment for an underlying cause of behavior is needed before prescribing antipsychotic medication for symptoms of dementia. [60] Antipsychotics in old age dementia showed a modest benefit compared to placebo in managing aggression or psychosis, but this is combined with a fairly large increase in serious adverse events.
Other symptoms may include restlessness, increased sweating, and trouble sleeping. [55] Less commonly there may be a feeling of the world spinning, numbness, or muscle pains. [55] Symptoms generally resolve after a short period of time. [55] There is tentative evidence that discontinuation of antipsychotics can result in psychosis. [56]
Other symptoms may include restlessness, increased sweating, and trouble sleeping. [25] Less commonly there may be a feeling of the world spinning, numbness, or muscle pains. [25] Symptoms generally resolve after a short period of time. [25] There is tentative evidence that discontinuation of antipsychotics can result in psychosis. [26]
Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia, [2] [3] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine. [4]
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