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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Preliminary clinical data suggests ginger may be effective for treatment of nausea and/or vomiting in a number of settings. [20] [21] [22] Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care setting in hospital as a rescue therapy for emesis. [23]
With respect to medications, pyridoxine or metoclopramide are preferred. [4] Prochlorperazine, dimenhydrinate, ondansetron (sold under the brand-name Zofran) or corticosteroids may be used if these are not effective. [3] [4] Hospitalization may be required due to the severe symptoms associated. [9] [3] Psychotherapy may improve outcomes. [3]
“Zofran is an anti-nausea medication,” says Qing, and it’s typically used preventatively. Zofran is an antiemetic that works by blocking the chemical that causes nausea and vomiting, per the ...
The preferred treatment in those with mild to moderate dehydration is oral rehydration therapy (ORT). [24] For children at risk of dehydration from vomiting, taking a single dose of the anti vomiting medication metoclopramide or ondansetron, may be helpful, [55] and butylscopolamine is useful in treating abdominal pain. [56]
Another subclass consists of drugs selectively acting at the 5-HT 3 receptors, and thus are known as 5-HT 3 antagonists. They are efficacious in treating chemotherapy-induced emesis and postoperative nausea and vomiting. [1] They include, but are not limited to: Dolasetron; Granisetron; Ondansetron; Palonosetron; Tropisetron
Metoclopramide is commonly used to treat nausea and vomiting associated with conditions such as uremia, radiation sickness, cancer and the effects of chemotherapy, labor, infection, and emetogenic drugs. [5] [12] [13] [14] As a perioperative anti-emetic, the effective dose is usually 25 to 50 mg (compared to the usual 10 mg dose).
5-HT 3 antagonists are most effective in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV), especially that caused by highly emetogenic drugs such as cisplatin; when used for this purpose, they may be given alone or, more frequently, with a glucocorticoid, usually dexamethasone.
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